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you can probably run Gemma4 26B on your card also at 4 bit. World of a difference compared with 12B.
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Where does “big model highly quantized” start getting worse than “smaller model less quantized”? Is there a general formula or is it just trial and error?
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paper is a bit old, but matches current empirical recommandation: a good starting point is the biggest model you can fit at 4 bit

https://arxiv.org/abs/2212.09720

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Have you tried qwen 27b q4_K_XL? It's a little bigger than the 4080 but not too much
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