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It's the only thing he could've done if he wanted the books to stand the test of time
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No, a useful language can be just as understandable in the far away future, but also way more approachable in the now/near future
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There are M/MIX assemblers and interpreters you can download and run - in some ways they're better than "real" programming languages because they're explicitly for instruction so usability concerns like package managers and build automation support don't get in "the way" of operating them.
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I agree with that opinion. He started writing TAOCP in 1968, and could have switched to Pascal in 1972.

Pascal is simple and clear, and can be translated easily to anything from LISP, Fortran, Python to C or C++ (in fact, subsets of Pascal are often used as sample language in books about compilers, including in Pascal inventor N. Wirth's own compiler book (which, unlike Knuth's, was completed timely):

Wirth, Niklaus, Compilers (1996), 101pp., 2rd revision, 2017, online: https://people.inf.ethz.ch/wirth/CompilerConstruction/Compil..., last accessed 2026-07-07).

It does not matter that Pascal is not much in use anymore, because due to its readability, it's timeless. It nearly reads like English prose, yet is automatically executable. It has also been standardized, and there is a book-sized language description available, as are several -- commercial and open source -- implementations.

In contrast, his pseudo-assembler is arcane. Whenever I wanted to implement an algorithm following Knuth TACOP, I had to work off his English pseudo-code description rather than the associated pseudo-assembler code.

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Whould would you have preferred?
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consider the alternatives. it could have been written in PL-1 and rapidly become dated. or it could have been written in a slightly higher level custom language and that would also have to be taught and would be less clear about what was going on under the hood. or a kind of pseudo-code that would also admit ambiguity. or it could have been rewritten in pascal, and then java, and then javascript and then rust.

given the timespan and the focus on complete analysis of running times and not just asymptotics, in the end maybe it wasn't so terrible a choice.

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Well, even as-is, it turns out that the kind of assembly language that Knuth originally wrote it in itself had a very short lifespan. MIX assumes a single accumulator register for arithmetic, which hasn't been a common processor architecture since around the 1980s. MMIX is redesigned to be more RISC, but it also uses a dynamic register window concept (which itself I think was only used on Itanium, and we all know how that architecture went down).

And unfortunately, for a lot of modern algorithms, you're going to have dive into SIMD-like algorithms, something MMIX doesn't have. Also, a lot of modern processors have a decent suite of bitwise operations (e.g., count leading/trailing zeros/ones, popcount) that is also missing from MMIX.

The programming languages that are in favor may change from decade to decade, but so to does most of the assembly language techniques.

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MMIX uses register windows to make stack frame pointer offsets unnecessary when referring to PUSHed arguments. Don is trying to make the algorithms understandable and correct, and by hiding some details that are handled efficiently by compilers (keeping track of FP and offsets), it benefits the human reader.

Don's first computer was the IBM 650 https://en.wikipedia.org/wiki/IBM_650?useskin=vector see also http://ed-thelen.org/comp-hist/KnuthIBM650Appreciation.pdf so MIX was a simplified version of the 650 because, well, it's well-defined and simple -- and Don knew a popular IBM machine very well. And there's this, in Vol 1:

This series of books is affectionately dedicated to the Type 650 computer once installed at Case Institute of Technology, in remembrance of many pleasant evenings.

MMIX is for all you youngsters who think RISC is all the rage ;-) and I think he does an admirable job creating a fully-defined machine that does use more modern hardware techniques. The fact that he fully defines his underlying machine is exactly correct, because it lays the foundation for precisely expressing the algorithms, and for giving Time and Space (runtime) estimates.

I believe it's fundamentally incorrect to think of these abstract machines as 'assembly language' but rather, I think, they define a stable foundation onto which accurately described algorithms can be expressed. You're supposed to 'play computer' and follow along -- step by step -- to understand the deep details of the algorithms.

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Sparc and Xtensa also have register windows, although each has a slightly different implementation.

They were all the rage for a while, because they make procedure calls fast but turn out to have subtle issues in highly-multithreaded scenarios.

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The Sparc and Xtensa register windows are fixed-size, not dynamic like Itanium's.
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