If you insist on firing guided missiles at ground targets from a drone that returns to base you're never gonna be able to compete on cost.
If the cheap solution involves having troops only a dozen miles away from the enemy, then you're going to take casualties, and funeral costs are FAR more expensive then the cost to buy a large bird and fly it from a 100+ miles away.
Guided missiles specifically are insanely pricey by comparison to the warhead alone; just for the possibility that your slow, vulnerable drone might be able to return (and be used again) you have to make very expensive engineering tradeoffs, and even when the thing comes back you have to repair and service it, too (and stock it up with more expensive missiles).
Depends on the goal. If the goal is to make high precision strikes - one big drone with tons of capabilities. If the goal is the terror strike campaign like russian - cheap Shahed drones are the best.