Science means the pursuit of knowledge. It doesn't mean "only believing proven things". If we're going to be rude, lets at least take the time to be right.
You dont seem to understand what proof means. Human brain is made of matter, matter can be arranged to make a thing that reproduces human brain properties. What's the confusion here? I say its unscientific because it places the human brain beyond the scope of what can be operated on. Not having the knowledge or tech yet to achieve that is irrelevant since we have an existence proof.
Even if we accept your premise, and not everyone does, the confusion is whether we're capable of creating an equivalent arrangement, even in principle, using alternative materials.