Personal laptop use with Ada Lovelace or Ampere family NVIDIA GPUs (did you mean this or CUDA, i couldnt tell), personal desktop use with unusual peripherals, dependency on ports, existence and competition of FreeBSD etc. I love OpenBSD's code philosophy (they were the first to introduce a lot of security techniques[1]) and the programs they produce, OpenSSH is a lifesaver, and I use doas for its low footprint on my Linux machine. Still, they have a convulated install process, dubious hardware and software compatibility that is better solved in the Linux world today.
[1]: https://www.openbsd.org/innovations.html