If you treat evidence as in the law of excluded middle, then yes. But if you are ready for a probabilistic evidence, then the article is a piece of evidence.

It chains Fermi Paradox, and our lack of knowledge how to do metallurgy in space. They both combined raise probability of impossibility of Von Neumann probes. It is not a proof that rules out Von Neumann probes, but it raises doubts about them.

The thesis was, “I would like to suggest that the hardest part is the one that gets a single sentence: ‘mines local material and builds a copy.’” And so naturally the points in the article are only trying to support that point.

The closest we get to what this thread is talking about is the concluding remark on the Fermi paradox. Which doesn’t rest on the idea that it’s a practical impossibility; just on the suggestion that it may be hard enough that we can’t just assume civilizations that are in principle capable of building them are likely to actually do it.