"Israel or North Korea, both of which try to be self-sufficient" - Neither of them do any such thing though. From a quick search Israel imports about 80% of their calories though they also export some food they are heavily reliant on imported grains and meat. North Korea is obviously harder to get information on but it imports large amounts of food from China.

Both North Korea and Israel are notable (compared to space) for their dense oxygen rich atmospheres, accessible large reservoirs of water, access to solvents/lubricants, and a generally "shirt sleeves" environment for workers. Asteroids, the Moon, and deep space don't really have these things. So you're not just bootstrapping an industrial facility at those locations but all the basic infrastructure that industry requires to exist.

With space manufacturing the first widget out of a factory costs trillions of dollars. There's also few if any raw materials that are far more abundant in space than here on Earth (at orders of magnitude smaller cost).