This is generational debt for a Kardashev Type III civilization. If there are individuals who are being charged "the whole of the GDP the human race has ever produced", then Amazon is claiming the rest of the world owes them a fairly significant portion of the galaxy if you consider the entire billing claims being made here.

There have been some big billing errors in the past but I wouldn't be surprised this is a new record. I know I've seen people charged around 92 quadrillion, which is a rounding error from underflowing a signed 64-bit integer with pennies, but those stories are usually isolated individuals. It sounds like the aggregate error here may comfortably exceed that. Hard to tell how widespread this is; as a data point my ~$2.00/month spend on S3 seems to still be billing correctly, so it must not be affecting everyone. But a few trillion here and a few trillion there and you get up to those quadrillions pretty quick.