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It's rather broad right now. I started reverse engineering a mac app and it started reading some binary data and then quickly told me to switch to Opus 4.8 to continue, because the guardrails kicked in.
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Try GPT 5.6 Sol if you haven't yet.

I recently created a patch for Riftborne via static IL patching and Fable 5 outright kept refusing to do it, no issue whatsoever with GPT 5.6 Sol lol.

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I am very excited for a future where all software is by default modifiable, even shipped binaries, via patches or trampolining, or trickery I don't even know the name of.
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It's essentially here, I've had success with gpt-5.6 and Ghidra MCP
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