A quick test (C, clang) gives me that a binary depending on 1000 shared libraries, each containing a single function returning an integer, with a main function summing up the results of all those functions, takes ~270ms to run from the dynamic linker overhead. So you'd definitely want a good chunk below thousands.

(a process with 100 shared libraries takes 6ms to run, which is a lot better (0.9ms for 1 library, for reference), but, especially with in-place patching skipping work on unchanged values, static linking still has a good shot at beating dynamic linking, especially if you run the binary multiple times)

Incremental compilation generally already depends on its stored intermediate data not getting corrupted, and the final binary need not be any differently handled in that aspect.

If you choose to build static or dynamic libraries, I expect you’d still get to do that, and I expect as long as those don’t change and only the main binary needs patching it’d work the same. (Though I’m waiting for the next tagged release to really try it out myself, so that’s not like a guarantee or anything.)