Retatrutide has a specific mechanism for clearing liver fat (glucagon) which makes it one of the most effective ways to treat T2D. This is the 3rd agonist not found in semaglutide or tirzepatide.
replySemaglutide clears liver fat? I had no idea. I’m curious to know more about your protocol
replyMy protocol was to take semaglutide
replyAs a consequence I ate less. Weirdly, I think I eat more sugar now but my total calorie intake is lower. I eat more sugar because sometimes it's the only thing that seems palatable or I'm trying to counteract the hypoglycemia feelings.
I have this same reaction sometimes, I don't have the desire to eat a full meal with protein and fat, but a little candy is palatable. It's probably not a good idea overall to be honest, it would be better to just "save up" hunger for a more balanced meal.
replyAre you implying the medicine did it or does the medicine just make you eat less which cleared it? Like is there an MOA of the drug itself?
replyYes the medicine does it. It's attacking T2D via several pathways, but in the case of Reta the glucagon is doing the heavy lifting of clearing liver fat.
replyThis extra receptor is why Reta is a triple agonist unlike semaglutide (single glp1) or tirzepatide (glp1+gip double agonist).