There was a vaccine over 20 years ago. It was discontinued due to low demand.

https://www.cdc.gov/lyme/about/lyme-disease-vaccine.html

Looks like there are clinical trials of a new vaccine, maybe demand will be higher this time around. The link also mentions a PrEP-type of treatment, which would be given seasonally. My bet is on that one, big pharma loves nothing more than a treatment that isn't quite a cure, but requires constant maintenance.