Of course! Most people in the computing world work way higher up the ladder of abstraction. I suspect a small minority of working software engineers know what an ISA even is.
I did some contract work in web development for a time. It is staggering how few people understand how the javascript they write gets executed on the machine. People don't understand pointers, or virtual machines, or in many cases how JS bundlers work, despite using them daily.
In some ways, this is a sign that our abstraction layers have been a great success! People can program for the virtual javascript machine, without needing to understand how the actual machine works, or how it emulates javascript. Is this the future we wanted? I'm not sure. But it's here.
To the extent that Raspberry Pi shipped a microcontroller that can literally be either RISC-V or ARM (indeed, one of each at the same time I think?)
RISC-V, it seems to me, lives in that cognitive space occupied by things like: open source, open weights, C, HTML, ethernet, Greggs sausage rolls and VHS.
Far from optimal, obviously flawed, and could change human society for the better. Ubiquity is inevitable.