I have AdGuard DNS set up (mainly use HaGeZi lists) for system wide blocking + AdGuard content blockers to catch some web ads and annoyances that cannot be caught via DNS.
Works very well, it’s been a good long while since any ad cheapened my web experience.
Also a big Wipr fan, and generally a fan of the indie dev behind it too because it works so well. They’ve been responsive over email so you might be able to request a feature
For those reading this, it does not work with Firefox (or anything not safari it seems). Wish I had looked that up before excitedly purchasing it lol but so it goes, seems like a good project so I’m considering it a $5 donation
Edit: looks like starting with ios26 they have “filtr” mode which extends more broadly to other apps but “stick to safari for best results”