The one thing I use the most, and how I found it in the first place is that it allows me to combine key presses with mouse gestures/movements. In particular it allows me to move/resize the windows under the cursor just by pressing a key combination and moving my mouse. Many many years ago I used to use AutoHotkey on Windows for this functionality and was missing it when I switched to Mac.

Another thing I've configured is scrolling through a key press and dragging the mouse. Or opening a floating menu by using the thumb button on my MX Master3.

And that's only mouse functions, I have a bunch of other shortcuts/remappings/automations, many of which run only for specific apps.

Have a look in the forum - it's a gold mine and a lot of people have shared their presets.