It definitely matters, if you're intending to run a Claude Code/OpenCode style agent workflow. Most of those harnesses start with 8-12k token contexts, which is a lot of prefill for a Mac but cheap for a CUDA GPU. The GPGPU compute on the fastest Macs is still trailing behind Nvidia's laptop GPUs; the highest-bandwidth Apple Silicon chip (now the M5 Ultra) has ~7x lower memory bandwidth than a single B100 card.
There's a good reason why Apple Silicon isn't to be found anywhere in the datacenter buildout. It's nonviable for training, and wastes electricity running real-world inference workloads.