> If you maintain the pairing with the statement about the concentration in the honey varying, it's somewhat harder to argue that it is overblown.

Those are two separate worries connected by an "and". I'm not arguing worry #2 is overblown.

And it sounds like the problem of variance is that it isn't small. If one batch can be 5x as strong as another (made up number), then even a pretty good medicinal response curve leaves you vulnerable to that much variance.