I think it's fair to debate whether it's a good thing that, as I heard it put once, "everything is wire fraud" (i.e. lots of crimes require lying on documents that are sent electronically and thus become federal crimes), but I see zero reason to think that committing academic fraud (which, again, is done for personal gain and causes real, measurable harm to others) is any less of a crime than lots of other things that are prosecuted as wire fraud.
The only thing that really works is a culture where this rarely if ever happens, because of the peer respect and self-respect of academics.
I'm not convinced that academic institutions are actually self-policing, it may not even be correct to assume they each act as one coherent entity. There are a lot of incentives in play which may not be obvious from the outside.
<apologies for yet another anecdote from way back when>
Many decades ago during my PhD I was in working in a chemistry lab when a colleague had an accident which caused a minor explosion, big enough to blow both of the glass side panes completely out of his fume hood.
With hindsight he was extremely lucky to have only minor injuries, he was peppered with tiny cuts from the flying glass and temporarily deaf from the bang.
I called for an ambulance, which seemed like a reasonable response.
The first prof on the scene (not our prof though!) came in and immediately asked "who phoned for the emergency services?", so I said it was me. He then gave me a bit of a telling-off, ending with him saying "and now the press will find out!" before he stormed off.
I remember thinking "wtf?! my colleague has just blown up our lab, and your top concern is that it will be in the newspapers"...