Depending on what sort of important you're talking, those ICs don't have the usual "something important" environmental specs, like an extended temperature range, or certification for automotive use or safety critical applications, for one thing.
>Why wouldn't a person build that into the heart of something important?
Because it's inexpensive and not designed to be tamper-resistant. If preventing this type of thing is your goal there are chips out there designed to break irrepairably if tampered with.
Rp2350s are advertised as having quite a few anti-tamper functions. They had a bounty when it launched to find similar vulnerabilities and they worked to patch the ones that were found. This is a lot more credible than a lot of advertised anti-tamper features.