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Why wouldn't those be possible to reproduce?
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"assign all these pointers to the correct types, a wrong guess leads to different COMDAT folding"

"get the order of local variables in this function right, otherwise the register allocation doesn't match. Oh and there's 150 local variables just in this function, good luck trying them all"

"Find out the translation unit boundaries exactly (assume there's no pdb otherwise this is trivial) and after doing so, figure out the order they were compiled in, otherwise it won't match"

"brute force the compilation flags for the project and if you're done, also bruteforce it for the CRT or any other middleware which usually came prebuilt so it doesn't match the main game"

Should I continue;)

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Indeed it's a shitload of work. It's also possible and has been done. You don't have to only use global brute-force - you could also reverse engineer the compiler. The OOT/MM decomps achieved completeness without //COMPILERDIFF.
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