And yes if you have a pdb / an Od build then things are much easier, I was assuming arbitrary game i.e. release binaries.
The "knowledge laundering" approach you describe might help in reconstructing headers, class layouts and function names which is a godsend although I don't think it would be enough to get a match. Getting functionally equivalent code is muuuch easier (although there's the problem of "how do you verify that without running every function")