Never had to worry again about sequencing updates where the update changed the database schema and I had a cluster of 6 web servers. Never had to worry anymore about long ass load times because the web servers were in 3 colos and wordpress wouldn't play nice with local read only mysql replicas. No more worries about why pingbacks and comments keep showing up in the database even those those features were turned off; at least they weren't showing up in a moderation queue, but still.