Amps determine how hefty a cable needs to be, not volts. Volts mostly determine how thick the insulation needs to be.
reply14 gauge wire is basically all you need to carry 10A safely for an extended period of time regardless the voltage. It doesn't matter that you are carrying 120KW.
The proof of this is in EV charge cables. Those bad boys can carry up to 350kW. Yet the cables are often thinner than you might expect. How do they do this? It's by using high voltages (around 900V) which cuts back the amps to around 300->400.
Tesla's chargers peak (or used to) around 600V which has required them to have much beefier cables to handle the high current.
I get that. I'm pretty skeptical that 120 KW going through the last panel doesn't cause damage, and in the "multiple miles chained together" (to quote op) many MW going through the panel at the end of the chain doesn't run into some sort of issue in the real world. Even small percentage losses turn into a lot of heat or other issues at that scale.
replyIf it doesn't why not just make the whole 100 mile stretch of canals discussed a single very long daisy chain of panels, and still address the concern of the OP in terms of extra material for conductors?