Selfish gene theory is discredited as reductionist and mostly wrong. You can't ignore the whole organism.
replyI get its just a framework to understand what is happening, but I always hate the phrasing of describing a 'decision' to a process like evolution. There are no decisions being made in the process, just a series of outcomes that lead in a direction
replyEvolution is literally just the observation that there are lots of things that self-replicate.
replyThat's it. That's the entire thing. Plus some nuance about things that self-replicate faster than other things...
It occurs at all levels. Amyloid protein in Alzheimer's patients is self-replicating. So are cells. So are individual parts of cells. Sometimes things replicate by being parts of a larger thing that replicates, sometimes they don't. It's all one big chaotic tangled mess with no particular purpose or design. Human cells evolve, so do humans, so do human societies. So do rocks.
I mean, that might be the fundamental driver of evolution, but we have observed a lot of other emergent properties that happen because of that process, and those observations form our understanding of what those self-replicating things lead to.
replyNo, evolution is not an observation that there are things that replicate. Darwin's view, which has survived mostly intact, is that there is replication with variation and that more fit individuals replicate at a higher rate ("survival of the fittest" isn't a correct description; plenty of less fit individuals do replicate, but they contribute very little to the population genetics in the long run)
replyAnd amyloid protein doesn't self-replicate. An instance of the misfolded form causes other folded proteins of the same type to transition to the misfolded form. It's a form of catalysis, not self-replication.
Seems like splitting a hair. In a world abundant with other amyloids, they'd self-replicate. Cells likewise need nutrients and a favorable environment.
replyIn retrospect I conclude you're right (that it's splitting a hair). I went back and some literature does use the term self-replication although at least within my academic circles, we consider autocatalyzed template matching simpler than self-replication.
replyRocko can't have kids, because Rocko is just a stupid rock.
replyCrystals catalyze their own expansion in a suitable solution.
replyPossibly a reference to A.G. Cairns-Smith, who speculated about evolving clay crystals. (They can sit in a stream and accumulate minerals, and reproduce that way.)
replyIndeed, I’ve heard so many people misunderstand it because of this type of wording. Like there is still some plan and series of steps we’re following - which really misses the whole point and why it’s worth knowing in the first place
replyOh, fair point, I did the pathetic fallacy (too). Beneficial thing, then.
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