Reversed an old video game pretty extensively for me. Got it running in 30 minutes, then patched some bugs, reversed the entire game logic VM and rendering pipeline, and we're now in process of expressing game logic as Lisp and upscaling assets for rendered that it already made to operate at 4x its hardcoded resolution...

Starting point was literally original installer copied over from a CD, which I hold on to and dug up from an old hard drive, plus a short prompt asking to make it work. Installing Ghirda and developing a whole framework for patching the binary, as well as substituting DirectDraw with its own DLL shim, was Claude's own invention.

It depends on what you're reversing. It tends not to like DRM-shaped things or security-sensitive things (for a very vague definition of "security-sensitive"), but e.g. game engines are fine. (For the things it doesn't like, dropping down to Opus 4.8 or 4.6 usually works)

Works fine for me. I didn't explicitly say decompile but it had no issue digging into executables to give me information on how it and various file formats were designed.