I've done the same with some old games I used to play, SimTower and Oregon Trail II, both fully decompiled and now running natively on modern macOS.

I'm going to try create an interactive twitch stream where viewers can play the game through the stream and other non-player viewers can trigger events in the game via points.

Crazy time we live in.

Edit, you come to really understand the game in the process, and why things happen and how to better play the game. And occasionally come across bugs, dev assets, assets never used, or assets all coded up, but code never triggered.

Surprisingly, no. I've been using Fable and Astra both to orchestrate decompilation of a relatively modern game (delivered via Steam) and they have no qualms about it.