This is not me being snarky, but all meaningful questions can be settled empirically---e.g., "what happens to my body if I jump off the cliff". But empirical trials have a cost (time, money, irreversibility etc.) and we model and predict because it's cheaper than the trial.
The idea that all meaningful questions can be answered empirically is known as "verificationism" and is philosophically quite dubious.
This is a logical positivist view, that not everyone agrees with.