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It was a systematic review, not a “singular ‘research study’”. A newer 2019 Cochrane review[0] found about the same:

> The evidence was limited in applicability and was incomplete. The included studies only presented data on gingivitis, plaque, and adverse events; most did not measure or report other important outcomes such as periodontitis or interproximal caries. … Additional use of floss or interdental brushes compared to toothbrushing alone may reduce gingivitis or plaque, or both, and interdental brushes may be more effective than floss. The evidence is low to very low‐certainty, and the effect sizes observed may not be clinically important.

[0] https://pmc.ncbi.nlm.nih.gov/articles/PMC6953268/

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I am highly skeptical. In my younger years, I brushed regularly but did not floss at all. After dealing with a surprising number of cavities over a short period of time, I decided to just start flossing, morning and night.

Not only does flossing remove quite a bit of, er... stuff... that toothbrushing does not seem to get, I have not had a single new cavity in 25 years. The only issues I've had were old fillings falling out, including one that cracked my tooth which required a crown. Not a lot of work considering the time span.

Obviously one person is not "data" but seeing as I am that one person, I'm going to keep flossing.

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