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  >if you are blowing fresh air into a room, or have the windows open, the filtration effectiveness of these units approaches zero pretty rapidly
Even with an open window, if (say) the air purifier and the window have a flow of 200 CFM, then the air will still be twice as clean (ie half as many pollution particles). I would say that's still worth doing!

Most people would just leave the window open <1", which keep CO2 down yet air purifiers still work well.

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> ~50-100W of power

That sounds too high? An AirFanta 3Pro on "2" is 141 CFM at under 5W https://www.jefftk.com/p/running-an-air-purifier-on-batterie...

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That’s the design appeal of ionizers like BlueAir (not most ionizers, but specially those designed to supposedly prevent ozone production). They comparatively sip power while getting the same measured reduction in particulates and ozone.
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