Yes, but if you can make a reliable experiment that disagree with the doctrine, it will change, even if everyone hates the idea. In particular https://en.wikipedia.org/wiki/Wu_experiment
[0] I personally don't think Science concerns itself whether things are real, only whether the result of model and realness match, but that's what we are discussing here.
If you read late Wittgenstein or Karl Popper, you will find that science is a useful simplification. Rorty is boring and not useful, but he kills any sort of Realism.
The 3 gigantic holes:
1. It's all language. (Wittgenstein)
2. The edges of systems do not connect with each other.
3. There are exceptions to everything.
I know that might seem a bit generic, but these are the major flaws in the philosophy of science.
I was a true believer too.
If you ever want to learn a ton about science, read Popper. He tortures himself, but he's also scientific meta.
I guess if/when we discover a theory of everything then we could claim "this is real/reality", but what would that even mean other than modelling reality/outcomes with 100% fidelity?