The only place it makes sense is personal tech and computing, where USB chargers are cheap and ubiquitous, with technology replacement in 2-5 years instead of 5-10 for standard appliances.
On the usage side for instrumentation, avionics etc. it is usually 28 VDC.
2. Nearly no equipment uses 120VDC by itself, so you would need specialized DC-DC converters that can deal with the 120VDC input to go down to usual voltages like 48VD, 24VDC or 12VDC