Not really, no. If you're running an application server, then your entire app can get compromised if there's a security exploit in any of your app code, your web server, your kernel, your hypervisor.

Defense in depth says that simply compromising your application code shouldn't provide access to the physical hardware you're running on, and that's hopefully the case, but it doesn't mean your app is not hacked. It just hopefully means that a hack on your app code doesn't automatically give the attacker access to your entire company.