There are now Switch 2 emulators that can run any dumped game on PC/Mac etc. https://emulation.gametechwiki.com/index.php/Nintendo_Switch...
Most Switch 2 games are getting dumped, including the just released Ocarina of Time Remake https://imagepaste.org/i/kx5c925r.png
As I mentioned in my comment there is a native Switch code compiler for Mac, so not emulation https://github.com/seedds/nxnative
I'll believe that when there's an open ecosystem of state-of-the-art ARM (or RISC-V) devices based on industry consortiums reference specs. Until then, it's device trees all the way down or waiting for Qualcomm to get their Linux shit together. Yeah, didn't think so.