Absolutely — the pedal steel is the obvious example. The entire notion of the upward country pedal steel guitar bend is actually a side-effect of the continuous behaviour of a pitch shifting mechanism that the original designer did not design it for, which has now evolved to create an entire genre.
I think as a musician one should maybe focus on playing instruments more than being dependent on products, but perhaps the balance is shifting more towards customisation than ever before.
This is one reason why some musicians (guitarists cough) collect multiple instruments. A telecaster makes you play differently than a les paul.