Any kind of auditory discrimination challenge someone has will lead to much higher cognitive load to interpret noisy transmissions. That cognitive load is a resource that could be better spent on other flight instruments and crisis situations.
Putting a design lens on, someone with APD an extreme user who, if properly made accessible to, would wind up improving everyone's experience not just their own.
I wonder if a switch to digital could keep transmitting on analog for legacy needs while having a second digital system be the primary one used.