If they ran out of fuel with 50 tons of payload it certainly begs the question of whether they will get to the goal of 100 tons of payload even with upgrades.
They also had engine fail on boostback. Reliability has been a persistent problem, they'll have to fix it for refueling and manned operations.
"The booster’s primary objective on Flight 15 will be executing a successful launch, ascent, stage separation, boostback burn, and return to the launch site for catch. This will be the first return and catch attempt for a Super Heavy V3 booster." [1]