There are populations that consistently outlive and the only other thing I would add is stress removal in the form of relatively simple life styles.
And I mean here both sacrifice the things you hold dear directly, or indirectly - which for us here is predominantly our careers and places of living.
Exaggerating a little bit to underscore the point: I could likely add years to my QALY lifespan if I moved to countryside, picked up more manual labor that required me to move my whole body, and went hiking in between going to the gym -- but, the things I value are found in cities, the work I like is white-collar, I hate hiking, and I also have people I love to support and lifespan-friendly labor generally doesn't pay enough.
To live a life that's even remotely healthy we have to dedicate a significant amount of the precious spare time we have just to undo some of that damage.
I do not believe we are predisposed to adopt sedentary lifestyles. As kids most of us are very active, but we are taught to be sedentary. Both academically and professionally we are most rewarded for sedentary activities: doing extra coursework, building your resume. Is it any surprise we develop a sedentary lifestyle when such a lifestyle is most rewarded?
These things are quite literally the leading causes of death and impairments in the west...
Are his therapies are over the top and lacking a bit of experimental rigor? Probably. Does he look healthy af? Definitely.
And to me he doesn't look healthy af. His skin is good, sure.
Or what happens when we stop them? Perpetual adolescence seems mainstream now. But it would be nice to know if some of these changes should be brought up as well as pushed back.
We don't - people inevitably age and die. All you can hope to do is postpone these shifts, and I suspect a large component in the timing is genetic, so there isn't a magical solution that will work for everybody just because it works for the guy posting about the one guaranteed solution for preventing ageing, because it's worked so far for him.