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>Running Windows 10 Enterprise IoT LTSC [...] have yet to encounter any issues.

It depends on the type of software a user runs. I installed Windows 10 LTSC on a friend's computer last year thinking she could run it for at least 5 more years and just ignore the newer Windows 11/12/whatever.

But she needed Intuit TurboTax 2025 and it requires Windows 11 and it's a hard requirement. The installer aborts on Windows 10. It's not a soft requirement like Adobe where they only support Windows 11 but their installer still runs on Windows 10. Autodesk Fusion 360 is another example that requires Windows 11.

I'm guessing if there's a future Windows 12, Intuit TurboTax will be aggressive about making it a requirement that forces the issue even though nobody wants to upgrade to it.

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Fusion 360 complains about Windows 10, but it still runs fine.
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I'd say that comes down to the difference between requirements (i.e. will it run at all, does it use features only found in win11) and support, and the developer's decisions around that. I can appreciate not supporting win10 even if it runs as they have a written or implied burden to make sure it keeps operating correctly for the lifespan, and that may include keeping test systems around or handling bugs that turn up in the OS that's getting reduced support itself, or other factors like drivers. Then there's the question of whether people would be willing to pay for a "your mileage may vary" level of support on something commercial.
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Only downside I've encountered using W10 IoT LTSC is that I had the temporarily change the currentbuild key (HKLM\SOFTWARE\Microsoft\Windows NT\CurrentVersion) in registry to 19045 to be able to install docker and WSL2.
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I thought it was 2032. I use IoT LTSC as well and I can second that this is a great OS and everything runs without issue.

I would add that I've also used Windows 11 IoT LTSC and that experience is very similar to Windows 10 IoT LTSC.

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I have Win11 Pro and have yet to encounter any issues
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