If 0.1% of people do it, then it probably isn't worth while. If it 10% of the audience, that needs to be focused on.
I am absolutely sure others can, but not me. I also think credit goes to far better encoders today than what we had 25 years ago.
Approaching 50, with less sensitive ears and a bit of tinnitus, I’m happy with the convenience of Bluetooth headphones and whatever format Spotify uses.
I use a dual A7X setup with a Sub10 Mk2 in a proper studio listening environment, and I can easily hear the difference between a low‑quality MP3 and a fully lossless WAV/FLAC. I do have trained ears, but even an untrained listener could probably notice that level of difference.
I use a pair of calibrated Genelec 8341 btw.